17958-43-9|Amabiline|Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1H-pyrrolidizin-7-yl)methyl ester|-范德生物科技公司

Amabiline

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names：
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7a-tetrahydro-1H-pyrrolidizin-7-yl)methyl ester
CAS号：
17958-43-9
MDL Number：
MF(分子式)： C16H19NO4 MW(分子量)： 289.33
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Amabiline
英文别名	Amabiline
CAS号	17958-43-9
Inchi	InChI=1S/C16H19NO4/c18-11-1-2-14-16(15(11)19)3-4-17(14)7-9-5-12-13(6-10(9)16)21-8-20-12/h5-6,11,14-15,18-19H,1-4,7-8H2/t11-,14-,15-,16+/m1/s1
InchiKey	DLYIURZCCWSUKD-MPESAESLSA-N
分子式 Formula	C16H19NO4
分子量 Molecular Weight	289.33
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Amabiline(CAS:17958-43-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Amabiline is an antimalarial alkaloid.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Senter TJ, Fadeyi OO, Lindsley CW. Enantioselective total synthesis of (+)-amabiline. Org Lett. 2012 Apr 6;14(7):1869-7[1]doi: 10.1021/ol300466a. Epub 2012 Mar 20. PubMed PMID: 22432912; PubMed Central PMCID: PMC3359844.

[2]Findlay AD, Banwell MG. A chemoenzymatic total synthesis of (+)-amabiline. Org Lett. 2009 Jul 16;11(14):3160-2. doi: 10.1021/ol901230w. PubMed PMID: 19586069.

[3] Boppré M, Colegate SM. Recognition of pyrrolizidine alkaloid esters in the invasive aquatic plant Gymnocoronis spilanthoides (Asteraceae). Phytochem Anal. 2015 May-Jun;26(3):215-25. doi: 10.1002/pca.2555. Epub 2015 Jan 27. PubMed PMID: 25645745.

[4] Likhitwitayawuid K, Angerhofer CK, Chai H, Pezzuto JM, Cordell GA, Ruangrungsi N. Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile. J Nat Prod. 1993 Aug;56(8):1331-8. PubMed PMID: 8229016.

[5] Letsyo E, Jerz G, Winterhalter P, Horn G, Beuerle T. Survey of pyrrolizidine alkaloids in seven varieties of Lappula squarrosa: An alternative source of heart-healthy vegetable oil. Phytochem Anal. 2016 Mar-Apr;27(2):133-9. doi: 10.1002/pca.2608. PubMed PMID: 26895990.

6: Edgar JA, Lin HJ, Kumana CR, Ng MM. Pyrrolizidine alkaloid composition of three Chinese medicinal herbs, Eupatorium cannabinum, E. japonicum and Crotalaria assamica. Am J Chin Med. 1992;20(3-4):281-8. PubMed PMID: 1471612.7: Hendriks H, Balraadjsing W, Huizing HJ, Bruins AP. Investigation into the Presence of Pyrrolizidine Alkaloids in Eupatorium cannabinum by Means of Positive and Negative Ion Chemical Ionization GC-MS. Planta Med. 1987 Oct;53(5):456-61. PubMed PMID: 17269067.8: Wiedenfeld H, Guerrero R, Roeder E. Pyrrolizidine alkaloids from Eupatorium portoricense. Planta Med. 1995 Aug;61(4):380-1. PubMed PMID: 17238090.9: Trigo JR, Witte L, Brown KS Jr, Hartmann T, Barata LE. Pyrrolizidine alkaloids in the arctiid mothHyalurga syma. J Chem Ecol. 1993 Apr;19(4):669-79. doi: 10.1007/BF00985000. PubMed PMID: 24249009.10: Williams MT, Warnock BJ, Betz JM, Beck JJ, Gardner DR, Lee ST, Molyneux RJ, Colegate SM. Detection of high levels of pyrrolizidine-N-oxides in the endangered plant Cryptantha crassipes (Terlingua Creek cat's-eye) using HPLC-ESI-MS. Phytochem Anal. 2011 Nov-Dec;22(6):532-40. doi: 10.1002/pca.1314. Epub 2011 Mar 24. PubMed PMID: 21433162.1

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