107767-55-5|Albifylline|1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione|-范德生物科技公司

Albifylline

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names：
1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS号：
107767-55-5
MDL Number：
MF(分子式)： C13H20N4O3 MW(分子量)： 280.33
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Albifylline
英文别名	Albifylline
CAS号	107767-55-5
SMILES	O=C(N1CCCCC(C)(O)C)N(C)C2=C(NC=N2)C1=O
Inchi	InChI=1S/C13H20N4O3/c1-13(2,20)6-4-5-7-17-11(18)9-10(15-8-14-9)16(3)12(17)19/h8,20H,4-7H2,1-3H3,(H,14,15)
InchiKey	NWXULHNEYYFVMF-UHFFFAOYSA-N
分子式 Formula	C13H20N4O3
分子量 Molecular Weight	280.33
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Albifylline(CAS:107767-55-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Albifylline is a xanthine derivates and anti-asthmatic agent. It may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. In addition, it improves microvascular blood flow in the liver.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Marzi I, Maier M, Herzog C, Bauer M. Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat. J Trauma. 1996 Jan;40(1):90-6. PubMed PMID: 8577006.

[2]Meskini N, Némoz G, Okyayuz-Baklouti I, Lagarde M, Prigent AF. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem Pharmacol. 1994 Mar 2;47(5):781-8. PubMed PMID: 8135854.

[3] Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S. Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Eur J Immunol. 1995 Jan;25(1):147-53. PubMed PMID: 7843225.

[4] Sinha B, Semmler J, Haen E, Moeller J, Endres S. Radioimmunoassays for cyclic AMP cross-react with phosphodiesterase inhibitors and buffer components. J Toxicol Methods. 1995 Sep;34(1):29-36. PubMed PMID: 7496044.

[5] Hand WL, Hand DL. Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cells. Antimicrob Agents. 1995 Jul;39(7):1574-9. PubMed PMID: 7492107; PubMed Central PMCID: PMC162784.

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