129556-87-2|Adefovir monophosphate|((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonic phosphoric anhydride|-范德生物科技公司

Adefovir monophosphate

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names：
((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphonic phosphoric anhydride
CAS号：
129556-87-2
MDL Number：
MF(分子式)： C8H13N5O7P2 MW(分子量)： 353.17
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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FMK10844-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	Adefovir monophosphate
英文别名	Adefovir monophosphate, Adefovir phosphate
CAS号	129556-87-2
Inchi	1S/C8H13N5O7P2/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-19-5-21(14,15)20-22(16,17)18/h3-4H,1-2,5H2,(H,14,15)(H2,9,10,11)(H2,16,17,18)
InchiKey	VQIHLCFUFNQXPS-UHFFFAOYSA-N
分子式 Formula	C8H13N5O7P2
分子量 Molecular Weight	353.17
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Adefovir monophosphate(CAS:129556-87-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) that works by blocking reverse transcriptase for the treatment of hepatitis B. Adefovir dipivoxil is not effective against HIV-1.
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危险性	Warning
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备注

[1]Lin RZ, Sun PJ, Tao Q, Yao J, Chen JM, Lu TB. Mechanism study on stability enhancement of adefovir dipivoxil by cocrystallization: Degradation kinetics and structure-stability correlation. Eur J Pharm Sci. 2015 Oct 10. pii: S0928-0987(15)30035-X. doi: 10.1016/j.ejps.2015.10.006. [Epub ahead of print] PubMed PMID: 26462447.

[2]Ning HB, Li K, Li W, Ding GQ, Xiao EH, Mao ZS, Kang Y, Shang J. [Adefovir dipivoxil effects on and related factors of blood phosphorus metabolism in patients with chronic hepatitis B]. Zhonghua Gan Zang Bing Za Zhi. 2015 Aug 20;23(8):590-3. doi: 10.3760/cma.j.issn.1007-3418.2015.08.007. Chinese. PubMed PMID: 26447622.

[3] Gu J, Sun R, Shen S, Yu Z. The curative effect of adefovir dipivoxil treating HBeAg negative chronic hepatitis B and treating HBeAg positive chronic hepatitis B combining interferon α-2b. Pak J Pharm Sci. 2015 Jul;28(4 Suppl):1493-7. PubMed PMID: 26431662.

[4] Zhu H, Yuan X, Tang L, Hu P, Cai D, Ren F, Huang W. [Clinical analysis of Fanconi syndrome induced by adefovir dipivoxil]. Zhonghua Gan Zang Bing Za Zhi. 2015 Apr;23(4):302-3. Chinese. PubMed PMID: 26427083.

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