82168-26-1|Adafenoxate|2-(1-Adamantylamino)ethyl (p-chlorophenoxy)acetate|-范德生物科技公司

Adafenoxate

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names：
2-(1-Adamantylamino)ethyl (p-chlorophenoxy)acetate
CAS号：
82168-26-1
MDL Number：
MF(分子式)： MW(分子量)：
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Adafenoxate
英文别名	Adafenoxate; Adafenoxato; Adafenoxato
CAS号	82168-26-1
Inchi	InChI=1S/C20H26ClNO3/c21-17-1-3-18(4-2-17)25-13-19(23)24-6-5-22-20-10-14-7-15(11-20)9-16(8-14)12-20/h1-4,14-16,22H,5-13H2
InchiKey	PLSMXIQMWYSHIV-UHFFFAOYSA-N
分子式 Formula
分子量 Molecular Weight
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Adafenoxate(CAS:82168-26-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Adafenoxate is a compound related to centrophenoxine, that has been found to act as a nootropic.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Stancheva SL, Alova LG. Biogenic monoamine uptake by rat brain synaptosomes during aging. Effects of nootropic drugs. Gen Pharmacol. 1994 Sep;25(5):981-7. PubMed PMID: 7835648.

[2]Hadjiivanova CI, Stancheva SL. In vitro and in vivo effect of the nootropic agent adafenoxate on the 5-HT1 sites in different rat brain structures. Gen Pharmacol. 1994 Sep;25(5):977-9. PubMed PMID: 7835647.

[3] Genkova-Papazova MG, Stancheva SL, Alova LG, Lazarova-Bakarova MB. Adafenoxate abolishes the amnesia induced by neonatal 6-hydroxydopamine treatment in rats. Methods Find Exp Clin Pharmacol. 1993 Jun;15(5):267-71. PubMed PMID: 8412411.

[4] Petkov VD, Markovska VL, Petkov VV. Effects of serotoninergic receptor antagonists and their combination with scopolamine on memory. Acta Physiol Pharmacol Bulg. 1991;17(1):21-8. PubMed PMID: 1815467.

[5] Lazarova-Bakarova MB, Petkova BP, Todorov IK, Petkov VD. Memory impairment induced by combined disturbance of noradrenergic and dopaminergic neurotransmissions: effects of nootropic drugs. Acta Physiol Pharmacol Bulg. 1991;17(1):29-34. PubMed PMID: 1667717.

6: Stancheva SL, Alova LG. Age-related changes of cyclic AMP phosphodiesterase activity in rat brain regions and a new phosphodiesterase inhibitor--nootropic agent adafenoxate. Gen Pharmacol. 1991;22(5):955-8. PubMed PMID: 1662175.7: Petkov VD, Mosharrof AH, Petkov VV, Kehayov RA. Age-related differences in memory and in the memory effects of nootropic drugs. Acta Physiol Pharmacol Bulg. 1990;16(2):28-36. PubMed PMID: 2281798.8: Petkov VD, Stancheva SL, Tocuschieva L, Petkov VV. Changes in brain biogenic monoamines induced by the nootropic drugs adafenoxate and meclofenoxate and by citicholine (experiments on rats). Gen Pharmacol. 1990;21(1):71-5. PubMed PMID: 2105261.9: Petkov VD, Mosharrof AH. Memory effects of the new derivative of the p-chlorophenoxyacetic acid adafenoxate compared to the effects of some cognition-enhancing drugs in rats. Arzneimittelforschung. 1989 Sep;39(9):1133-6. PubMed PMID: 2511850.10: Stancheva S, Kunova P. Effect of adafenoxate on different rat brain structures monoamine oxidase activity in vitro. Comp Biochem Physiol C. 1989;94(1):41-4. PubMed PMID: 2576744.1

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