77-46-3|Acedapsone|N,N'-Diacetyl-4,4'-diaminodiphenylsulfone|-范德生物科技公司

Acedapsone

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names：
N,N'-Diacetyl-4,4'-diaminodiphenylsulfone
CAS号：
77-46-3
MDL Number：
MF(分子式)： C16H16N2O4S MW(分子量)： 332.37
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Acedapsone
英文别名	Acedapsone; Acetamin; Atilon; Camilan; Rodilon; BA 2650; BA-2650; BA2650
CAS号	77-46-3
Inchi	InChI=1S/C16H16N2O4S/c1-11(19)17-13-3-7-15(8-4-13)23(21,22)16-9-5-14(6-10-16)18-12(2)20/h3-10H,1-2H3,(H,17,19)(H,18,20)
InchiKey	AMTPYFGPPVFBBI-UHFFFAOYSA-N
分子式 Formula	C16H16N2O4S
分子量 Molecular Weight	332.37
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Acedapsone(CAS:77-46-3):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Acedapsone, also known as Acetamin, Atilon, Camilan, and Rodilone, is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Olivares Sabournin R, González Segredo AB. [Bacteriologic study in patients with multibacillary leprosy treated with rifampicin and acedapsone]. Rev Cubana Med Trop. 1989 May-Aug;41(2):307-12. Spanish. PubMed PMID: 2486227.

[2]George J, Balakrishnan S. Blood dapsone levels in leprosy patients treated with acedapsone. Indian J Lepr. 1986 Jul-Sep;58(3):401-6. PubMed PMID: 3794408.

[3] Neelan PN, Sirumban P, Sivaprasad N. Limited duration acedapsone prophylaxis in leprosy. Indian J Lepr. 1986 Apr-Jun;58(2):251-6. PubMed PMID: 3543161.

[4] Russell DA, Worth RM, Jano B, Fasal P, Shepard CC. Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia. Am J Trop Med Hyg. 1979 May;28(3):559-63. PubMed PMID: 453449.

[5] Peters JH, Murray JF Jr, Gordon GR, Levy L, Russell DA, Scott GC, Vincin DR, Shepard CC. Acedapsone treatment of leprosy patients: response versus drug disposition. Am J Trop Med Hyg. 1977 Jan;26(1):127-36. PubMed PMID: 842774.

6: Levy L, Peters JH. Susceptibility of Mycobacterium leprae to dapsone as a determinant of patient response to acedapsone. Antimicrob Agents Chemother. 1976 Jan;9(1):102-12. PubMed PMID: 769667; PubMed Central PMCID: PMC429483.7: Russell DA, Shepard CC, McRae DH, Scott GC, Vincin DR. Acedapsone (DADDS) treatment of leprosy patients in the Karimui of Papua New Guinea: status at six years. Am J Trop Med Hyg. 1975 May;24(3):485-95. PubMed PMID: 1098496.

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