94899-83-9|711389-S|(S)-1-(2-(1-(1H-imidazol-1-yl)vinyl)-3,6-dichlorophenoxy)-3-(isopropylamino)propan-2-ol|-范德生物科技公司

711389-S

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names：
(S)-1-(2-(1-(1H-imidazol-1-yl)vinyl)-3,6-dichlorophenoxy)-3-(isopropylamino)propan-2-ol
CAS号：
94899-83-9
MDL Number：
MF(分子式)： C17H21Cl2N3O2 MW(分子量)： 370.27
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	711389-S
英文别名	711389-S; 711389 S; 711389S; S 1389; S-1389; S1389;
CAS号	94899-83-9
Inchi	InChI=1S/C17H21Cl2N3O2/c1-11(2)21-8-13(23)9-24-17-15(19)5-4-14(18)16(17)12(3)22-7-6-20-10-22/h4-7,10-11,13,21,23H,3,8-9H2,1-2H3/t13-/m0/s1
InchiKey	DROIRVKNZDBEFR-ZDUSSCGKSA-N
分子式 Formula	C17H21Cl2N3O2
分子量 Molecular Weight	370.27
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	711389-S(CAS:94899-83-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	711389-S is an antiarrhythmic agent.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Kotake H, Hisatome I, Hasegawa J, Yamasaki J, Kosaka T, Furuse T, Mashiba H. Inhibitory action of 711389-S on the electrical activity of rabbit sinoatrial node. Cardiovasc Res. 1987 Mar;21(3):197-20[1]PubMed PMID: 3652085.

[2]Ninomiya M, Tani T, Ueda M. Effects of S-1389 (711389-S), a new antiarrhythmic agent, on the conduction in perfused guinea pig hearts. Jpn J Pharmacol. 1989 Dec;51(4):555-62. PubMed PMID: 2615048.

[3] Iwaki K, Ishii M, Shinosaki T, Ueda M, Yonetani Y. Effect of 711389-S, a new antiarrhythmic agent, on myocardial energy metabolism in guinea-pigs and rats. J Pharm Pharmacol. 1988 Jan;40(1):10-6. PubMed PMID: 2896767.

[4] Nakajima S, Ueda M. Increase of the ventricular fibrillation threshold by 711389-S, a new antiarrhythmic agent, in guinea-pigs. Jpn J Pharmacol. 1985 Aug;38(4):436-8. PubMed PMID: 3840850.

[5] Kadowaki Y, Ohta T, Hotokebuchi N, Kimoto S, Haruna M, Nakao T, Ueda M, Nishi K. Actions of a newly synthesized compound (711389-S) on various types of experimentally induced arrhythmias in mammalian species in situ. Jpn J Pharmacol. 1988 Apr;46(4):359-72. PubMed PMID: 3404766.

6: Ninomiya M, Toyama J, Kodama I, Yamada K. Electrophysiological effects of 711389-S, a new antiarrhythmic agent, on guinea-pig isolated cardiac muscle. J Cardiovasc Pharmacol. 1984 Nov-Dec;6(6):1222-9. PubMed PMID: 6084783.7: Muramatsu I, Noda M, Nishio M, Fujiwara M. Mechanism of sodium channel block in crayfish giant axons by 711389-S, a new antiarrhythmic drug. J Pharmacol Exp Ther. 1987 Jul;242(1):269-76. PubMed PMID: 2441025.8: Hisatome I, Matsuoka S, Miyamoto J, Sawaguchi M, Omodani H, Osaki S, Kotake H, Mashiba H, Sato R. Blocking effect of 1389-S on the sodium current in isolated guinea-pig ventricular myocytes. Eur J Pharmacol. 1990 Apr 25;179(3):447-51. PubMed PMID: 2163858.

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