2454-11-7|Formebolone|11-alpha,17-beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde|-范德生物科技公司

Formebolone

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names：
11-alpha,17-beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde
CAS号：
2454-11-7
MDL Number：
MF(分子式)： C21H28O4 MW(分子量)： 344.45
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Formebolone
英文别名	Formebolone; Esiclene; Formebolona; Formebolonum; Formyldienolone
CAS号	2454-11-7
SMILES	C[C@@]12[C@@](C)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C(C=O)=C[C@]4(C)[C@@]3([H])[C@H](O)C2)=O
Inchi	InChI=1S/C21H28O4/c1-19-9-12(11-22)16(23)8-13(19)4-5-14-15-6-7-21(3,25)20(15,2)10-17(24)18(14)19/h8-9,11,14-15,17-18,24-25H,4-7,10H2,1-3H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1
InchiKey	AMVODTGMYSRMNP-GNIMZFFESA-N
分子式 Formula	C21H28O4
分子量 Molecular Weight	344.45
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Formebolone(CAS:2454-11-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Formebolone also known (confusingly) as formyldienolone, as well as 2-formyl-11α-hydroxy-17α-methyl-δ1-testosterone, is an orally active anabolic-androgenic steroid (AAS) described as an anticatabolic and anabolic drug. Formebolone counteracts the catabolic effects (control of nitrogen balance) of potent glucocorticoids like dexamethasone phosphate. A close analogue, roxibolone (and its long-acting ester variant decylroxibolone), shows similar antiglucocorticoid activity to formebolone but, in contrast, is devoid of activity as an AAS.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Pozo OJ, Van Eenoo P, Deventer K, Elbardissy H, Grimalt S, Sancho JV, Hernandez F, Ventura R, Delbeke FT. Comparison between triple quadrupole, time of flight and hybrid quadrupole time of flight analysers coupled to liquid chromatography for the detection of anabolic steroids in doping control analysis. Anal Chim Acta. 2011 Jan 17;684(1-2):98-11[1]doi: 10.1016/j.aca.2010.10.045. Epub 2010 Nov 9. PubMed PMID: 21167991.

[2]Leinonen A, Kuuranne T, Kotiaho T, Kostiainen R. Screening of free 17-alkyl-substituted anabolic steroids in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry. Steroids. 2004 Feb;69(2):101-9. PubMed PMID: 15013688.

[3] Cuatrecasas Membrado JM, Bosch Banyeres JM. [Study of non-hypophysiary growth retardation treated with formebolone]. An Esp Pediatr. 1985 Jan;22(1):27-32. Spanish. PubMed PMID: 3985494.

[4] Sperandeo F, Pedrazzini S, De Marchi G, Marre E. [Study on potential and real impurities present in a synthetic steroid: formebolone]. Boll Chim Farm. 1979 Apr;118(4):200-21. Italian. PubMed PMID: 454541.

[5] Pestalardi RV, Vàsquez OA, de Bujovic AT. [Effect of Formebolone in 16 infants with malnutrition]. Minerva Pediatr. 1977 Feb 18;29(5):297-302. Italian. PubMed PMID: 854006.

6: Gomarasca P, D'atri G, Cerutti S, Pedrazzini S. [Nitrogen balance in rats treated with Formebolone]. Boll Chim Farm. 1976 Dec;114(12):714-29. Italian. PubMed PMID: 1267976.7: Galimberti E, Forlani A. [Interaction of formebolone and natural cortico-adrenal extracts]. Boll Chim Farm. 1976 Sep;115(9):638-43. Italian. PubMed PMID: 1016618.8: Cerutti S, Forlani A, Galimberti E. Anticatabolic action of formebolone in the castrated rat treated with dexamethasone. Arzneimittelforschung. 1976;26(9):1673-7. PubMed PMID: 1036699.9: Gelli D, Vignati E. Metabolic studies with formebolone (2-formyl-17 (alpha)-methyl-androsta-1,4-diene-11 (alpha), 17 (beta)-diol-3-one) in humans. J Int Med Res. 1976;4(2):96-105. PubMed PMID: 799985.10: Esposito R, Pluvio M, Giordano D. Anabolic agents in kidney disease: the effect of formebolone on protein synthesis in patients with renal insufficiency or nephrosis. Curr Med Res Opin. 1975;3(1):43-5. PubMed PMID: 1116383.1

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