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51-64-9
  • Dextroamphetamine

  • names:

    (2S)-1-phenylpropan-2-amine

  • CAS号:

    51-64-9

    MDL Number:
  • MF(分子式): C9H13N MW(分子量): 135.21
  • EINECS: Reaxys Number:
  • Pubchem ID: Brand:BIOFOUNT
Dextroamphetamine
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中文别名 Dextroamphetamine
英文别名 Dextroamphetamine; D-Amphetamine; Dexamphetamine; (S)-Amphetamine; Dexamfetamine; Dexedrine
CAS号 51-64-9
SMILES C[C@@H](CC1=CC=CC=C1)N
Inchi InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
InchiKey KWTSXDURSIMDCE-QMMMGPOBSA-N
分子式 Formula C9H13N
分子量 Molecular Weight 135.21
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状 Solid powder
储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).
产品说明 Dextroamphetamine(CAS:51-64-9 ):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。
IntroductionDextroamphetamine is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. Dextroamphetamine, like other amphetamines, elicits its stimulating effects via three distinct actions first, it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) via trace amine-associated receptor 1 (TAAR1). Dextroamphetamine is discontinued now.
Application1
Application2
Application3
警示图
危险性 Warning
危险性警示
安全声明
安全防护
备注
[1]Check JH, Cohen R. Complete resolution of frozen shoulder syndrome in a woman treated with dextroamphetamine sulfate for chronic urinary urgency. Clin Exp Obstet Gynecol. 2015;42(5):679-80. PubMed PMID: 26524823.
[2]Check JH, Jaffe A. Resolution of pelvic pain related to adenomyosis following treatment with dextroamphetamine sulfate. Clin Exp Obstet Gynecol. 2015;42(5):671-2. PubMed PMID: 26524821.
[3] Roberts JK, Cook SF, Stockmann C, Rollins DE, Wilkins DG, Sherwin CM. A Population Pharmacokinetic Analysis of Dextroamphetamine in the Plasma and Hair of Healthy Adults. Clin Drug Investig. 2015 Oct;35(10):633-43. doi: 10.1007/s40261-015-0323-5. PubMed PMID: 26329917.
[4] Kenny JD, Taylor NE, Brown EN, Solt K. Dextroamphetamine (but Not Atomoxetine) Induces Reanimation from General Anesthesia: Implications for the Roles of Dopamine and Norepinephrine in Active Emergence. PLoS One. 2015 Jul 6;10(7):e0131914. doi: 10.1371/journal.pone.0131914. eCollection 2015. PubMed PMID: 26148114; PubMed Central PMCID: PMC4492624.
[5] Valvassori SS, Tonin PT, Varela RB, Carvalho AF, Mariot E, Amboni RT, Bianchini G, Andersen ML, Quevedo J. Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine. Bipolar Disord. 2015 Aug;17(5):507-17. doi: 10.1111/bdi.12299. Epub 2015 Apr 30. PubMed PMID: 25929806.
6: Kaland ME, Klein-Schwartz W. Comparison of lisdexamfetamine and dextroamphetamine exposures reported to U.S. poison centers. Clin Toxicol (Phila). 2015 Jun;53(5):477-85. doi: 10.3109/15563650.2015.1027903. Epub 2015 Apr 2. PubMed PMID: 25832473.7: Check JH, Cohen R. Severe headaches from intracranial hypertension (pseudotumor cerebri) abrogated by treatment with dextroamphetamine sulfate. Clin Exp Obstet Gynecol. 2014;41(2):211-3. PubMed PMID: 24779255.8: Check JH, Chan S. Complete eradication of chronic long standing eczema and keratosis pilaris following treatment with dextroamphetamine sulfate. Clin Exp Obstet Gynecol. 2014;41(2):202-4. PubMed PMID: 24779252.9: Check JH, Cohen R. Marked improvement of pain from long-term fibromyalgia with dextroamphetamine sulfate in a woman who failed to improve with conventional pharmacologic treatment. Clin Exp Obstet Gynecol. 2014;41(1):90-2. PubMed PMID: 24707694.10: Check JH, DiAntonio G, Cohen R. Dextroamphetamine sulfate, a very effective drug for pelvic pain relieved severe retroorbital stabbing pain in a woman with keratoconus who failed to respond to bilateral corneal implants. Clin Exp Obstet Gynecol. 2014;41(1):80-2. PubMed PMID: 24707691.
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