2751-68-0|Acetophenazine|1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone|-范德生物科技公司

Acetophenazine

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names：
1-[10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazin-2-yl]ethanone
CAS号：
2751-68-0
MDL Number：
MF(分子式)： C23H29N3O2S MW(分子量)： 411.56
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Acetophenazine
英文别名	Tindal; Acephenazinum; Acetophenazine.
CAS号	2751-68-0
SMILES	CC(C(C=C1N2CCCN3CCN(CCO)CC3)=CC=C1SC4=C2C=CC=C4)=O
Inchi	InChI=1S/C23H29N3O2S/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27/h2-3,5-8,17,27H,4,9-16H2,1H3
InchiKey	WNTYBHLDCKXEOT-UHFFFAOYSA-N
分子式 Formula	C23H29N3O2S
分子量 Molecular Weight	411.56
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Acetophenazine(CAS:2751-68-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Acetophenazine is discontinued (DEA controlled substance). It is an antipsychotic drug used in the treatment of psychosis. It is also used to treat hallucinations or delusions. It primarily targets the dopamine D2 receptor.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

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[2]Danielsson E, Peterson LL, Grundin R, Ogren SO, Bartfai T. Anticholinergic potency of psychoactive drugs in human and rat cerebral cortex and striatum. Life Sci. 1985 Apr 15;36(15):1451-7. PubMed PMID: 2858803.

[3] Tam SW, Cook L. Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes. Proc Natl Acad Sci U S A. 1984 Sep;81(17):5618-21. PubMed PMID: 6147851; PubMed Central PMCID: PMC391758.

[4] Issa AS, Mahrous MS. Titrimetric determination of some phenothiazine derivatives, with ferricyanide. Talanta. 1984 Apr;31(4):287-8. PubMed PMID: 18963590.

[5] Bigelow LB, Weinberger DR, Wyatt RJ. Synergism of combined lithium-neuroleptic therapy: a double-blind, placebo-controlled case study. Am J Psychiatry. 1981 Jan;138(1):81-3. PubMed PMID: 7192495.

6: Bhargava HN. Modification of pharmacological and toxicological effects of acetophenazine, chlorpromazine and thloridazine in morphine-dependent mice. Arch Int Pharmacodyn Ther. 1979 Mar;238(1):165-76. PubMed PMID: 573604.7: Jones GL, Woodbury DM. Spin-label study of phenothiazine interactions with erythrocyte ghost membranes: a possible membrane-mediated antisickling action. J Pharmacol Exp Ther. 1978 Oct;207(1):203-11. PubMed PMID: 702341.8: Iizuka Hadachi K, Halprin KM, Levine V. Histamine (H2) receptor-adenylate cyclase system in pig skin (epidermis). Biochim Biophys Acta. 1976 Jun 23;437(1):150-7. PubMed PMID: 7311.9: Hollister LE, Overall JE, Pokorny AD, Shelton J. Acetophenazine and diazepam in anxious depressions. Arch Gen Psychiatry. 1971 Mar;24(3):273-8. PubMed PMID: 5100621.10: Cahan RB. Acetophenazine for office treatment of paranoid symptoms. West Med Med J West. 1967 Mar-Apr;8(3):71-2. PubMed PMID: 6072166.

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