7492-32-2|Isopropamide|4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium|-范德生物科技公司

Isopropamide

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names：
4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium
CAS号：
7492-32-2
MDL Number：
MF(分子式)： C23H33N2O+ MW(分子量)： 353.5204
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Isopropamide
英文别名	Isopropamide, Chloroisopropamide, Piaccamide, Priazimide; Dipramid, Dipramide
CAS号	7492-32-2
SMILES	CC([N+](CCC(C1=CC=CC=C1)(C(N)=O)C2=CC=CC=C2)(C(C)C)C)C
Inchi	InChI=1S/C23H32N2O/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26)/p+1
InchiKey	JTPUMZTWMWIVPA-UHFFFAOYSA-O
分子式 Formula	C23H33N2O+
分子量 Molecular Weight	353.5204
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Isopropamide(CAS:7492-32-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Isopropamide (R5) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Abbas SS, Zaazaa HE, Abdelkawy M, Abdelrahman MM. Spectrophotometric determination of isopropamide iodide and trifluoperazine hydrochloride in presence of trifluoperazine oxidative degradate. Drug Test Anal. 2010 Apr;2(4):168-8[1]doi: 10.1002/dta.113. PubMed PMID: 20376832.

[2]Das Gupta S, Ghosh AK. Antidotal efficacy of isopropamide iodide in acute fluostigmine poisoning in mice. Pharmazie. 1985 Jul;40(7):499-500. PubMed PMID: 2864706.

[3] Gaginella TS, Bass P, Perrin JH, Vallner JJ. Effect of bile salts on partitioning behavior and GI absorption of a quaternary ammonium compound, isopropamide iodide. J Pharm Sci. 1973 Jul;62(7):1121-5. PubMed PMID: 4145953.

[4] Oi N, Miyazaki K. [Analyses of drugs and chemicals by infrared absorption spectrocopy. X. Determination of isopropamide in pharmaceutical preparations by compensation method]. Yakugaku Zasshi. 1967 Jun;87(6):739-41. Japanese. PubMed PMID: 4383924.

[5] Fiume S. [On the pharmacological effects of an association of haloperidol and isopropamide bromide]. Clin Ter. 1966 Oct 31;39(2):161-6. Italian. PubMed PMID: 5996918.

6: Magnin P, Frere M, Lapeyre B. [Notes on the action of isopropamide during delivery]. Lyon Med. 1966 Apr 3;215(14):973-7. French. PubMed PMID: 4379791.7: Zieliński M. [Cholinolytic and antihistaminic properties of isopropamide iodide]. Acta Pol Pharm. 1966;23(3):271-5. Polish. PubMed PMID: 4380485.8: Wambsganss E. [Experimental psychological research with the combined preparation "haloperidol plus isopropamide"]. Psychopharmacologia. 1965 Jan 14;7(1):61-71. German. PubMed PMID: 4378554.9: WAHL R, KEMPF F. [ISOPROPAMIDE (PRIAMIDE): ITS USE IN CONTRAST RADIOLOGICAL EXAMINATION OF THE COLON]. J Radiol Electrol Med Nucl. 1964 Aug-Sep;4

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